Hereditary Cancer Screening (CGx)

Reasons for Hereditary Cancer Screening:

• 2 or more family members diagnosed with the same genetic conditions
  
• Previous personal history of a genetic condition

Our cancer screening test is a medical examination designed to detect early signs of cancer before symptoms develop. Early detection of cancer can improve treatment outcomes and increase the chances of a successful recovery.

The screening process for cancer typically involves a physical exam, medical history review, and laboratory tests. Depending on the type of cancer being screened for, additional imaging tests or biopsies may also be recommended.

Common cancer screening tests include mammography for breast cancer, colonoscopy for colorectal cancer, Pap smear for cervical cancer, and prostate-specific antigen (PSA) test for prostate cancer. Other types of cancer, such as lung cancer or skin cancer, may require different screening methods.

Do not add to bag and proceed to checkout without approval from an Oxy-Gen Laboratory representative.

Panel Information

Turnaround time: 2-4 weeks for results
Collection Method: Buccal Swab or Saliva

DISCLAIMER: The service and fee selected above covers your pre-consult or post-consult telehealth visit with one of our genetic counselors. Prior to ordering this test, you must have a medical necessity that will be determined by our Genetic Counselors.

Additionally, you may still be eligible for the test if you do not meet your insurance's medical necessity. Oxy-Gen Laboratory will follow up with you in this case to discuss our self-pay cost of the test.

Genes:

Multi-Cancer Panel (84 genes) AIP, ALK, APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CASR, CDC73, CDH1, CDK4, CDKN1B, CDKN1C, CDKN2A, CEBPA, CHEK2, CTNNA1, DICER1, DIS3L2, EGFR, EPCAM, FH, FLCN, GATA2, GPC3, GREM1, HOXB13, HRAS, KIT, MAX, MEN1, MET, MITF, MLH1, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NF2, NTHL1, PALB2, PDGFRA, PHOX2B, PMS2, POLD1, POLE, POT1, PRKAR1A, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RB1, RECQL4, RET, RUNX1, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, SMARCB1, SMARCE1, STK11, SUFU, TERC, TERT, TMEM127, TP53, TSC1, TSC2, VHL, WRN, WT1

Common Hereditary Cancers Panel (47 genes) APC, ATM, AXIN2, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, CTNNA1, DICER1, EPCAM, GREM1, HOXB13, KIT, MEN1, MLH1, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PDGFRA, PMS2, POLD1, POLE, PTEN, RAD50, RAD51C, RAD51D, SDHA, SDHB, SDHC, SDHD, SMAD4, SMARCA4, STK11, TP53, TSC1, TSC2, VHL

Breast Cancer Guidelines-Based Panel (11 genes) ATM, BARD1, BRCA1, BRCA2, CDH1, CHEK2, NF1, PALB2, PTEN, STK11, TP53

Oxy-Gen Breast Cancer Panel (26 genes) Primary Panel (13 genes) ATM, BARD1, BRCA1, BRCA2, CDH1, CHEK2, NF1, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53

Add-on Preliminary-evidence Genes for Breast Cancer (13 genes) ABRAXAS1, AKT1, BRIP1, FANCC, FANCM, MRE11, MUTYH, PIK3CA, RECQL, RINT1, SDHB, SDHD, XRCC2

Breast and Gyn Cancers Guidelines-Based Panel (19 genes) ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, EPCAM, MLH1, MSH2, MSH6, NF1, PALB2, PMS2, PTEN, RAD51C, RAD51D, STK11, TP53

Breast and Gyn Cancers Panel (36 genes) Primary Panel (21 genes) ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, DICER1, EPCAM, MLH1, MSH2, MSH6, NF1, PALB2, PMS2, PTEN, RAD51C, RAD51D, SMARCA4, STK11, TP53
Add-on Preliminary-evidence Genes for Breast and Gyn Cancer (15 genes) ABRAXAS1, AKT1, CDC73, FANCC, FANCM, MRE11, MUTYH, NBN, PIK3CA, POLD1, RECQL, RINT1, SDHB, SDHD, XRCC2

Colorectal Cancer Guidelines-Based Primary Panel (20 genes) APC, AXIN2, BMPR1A, CDH1, CHEK2, EPCAM, GREM1, MLH1, MSH2, MSH3, MSH6, MUTYH, NTHL1, PMS2, POLD1, POLE, PTEN, SMAD4, STK11, TP53
Add-on Preliminary-evidence Genes for Colorectal Cancer (10 genes) ATM, BLM, BUB1B, CEP57, ENG, FLCN, GALNT12, MLH3, RNF43, RPS20

Prostate Cancer Panel (19 genes) Primary Panel (12 genes) ATM, BRCA1, BRCA2, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6, NBN, PMS2, TP53
Add-on Preliminary-evidence Genes for Prostate Cancer (7 genes) ATR, BRIP1, FANCA, GEN1, PALB2, RAD51C, RAD51D

Nervous System/Brain Cancer Panel (42 genes) Primary Panel (29 genes) AIP, ALK, APC, DICER1, EPCAM, HRAS, LZTR1, MEN1, MLH1, MSH2, MSH6, NBN, NF1, NF2, PHOX2B, PMS2, POT1, PRKAR1A, PTCH1, PTEN, RB1, SMARCA4, SMARCB1, SMARCE1, SUFU, TP53, TSC1, TSC2, VHL
Add-on Preliminary-evidence Genes for Nervous System/Brain Cancer (5 genes) BAP1, EZH2, GPC3, KIF1B, PTCH2
Add-on Hereditary Paraganglioma-Pheochromocytoma Genes (8 genes) MAX, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, TMEM127

Melanoma Panel (12 genes) Primary Panel (9 genes) BAP1, BRCA2, CDK4, CDKN2A, MITF, POT1, PTEN, RB1, TP53
Add-on Preliminary-evidence Genes for Melanoma (3 genes) BRCA1, MC1R, TERT

Renal/Urinary Tract Cancers Panel (32 genes) Primary Panel (25 genes) BAP1, CDC73, CDKN1C, DICER1, DIS3L2, EPCAM, FH, FLCN, GPC3, MET, MLH1, MSH2, MSH6, PMS2, PTEN, REST, SDHB, SDHC, SMARCA4, SMARCB1, TP53, TSC1, TSC2, VHL, WT1
Add-on Preliminary-evidence Genes for Renal/Urinary Tract Cancers (7 genes) BUB1B, CEP57, CTR9, MITF, PALB2, SDHA, SDHD

Sarcoma Panel (44 genes) Primary Panel (29 genes) APC, BLM, CDKN1C, DICER1, EPCAM, EXT1, EXT2, FH, HRAS, KIT, MLH1, MSH2, MSH6, NBN, NF1, PDGFRA, PMS2, POT1, PRKAR1A, PTCH1, RB1, RECQL4, SDHA, SDHB, SDHC, SDHD, SUFU, TP53, WRN
Add-on Preliminary-evidence Genes for Sarcoma (4 genes) CDKN2A, PTCH2, TSC1, TSC2
Add-on Diamond-Blackfan Anemia Primary Genes (11 genes) GATA1, RPL11, RPL15, RPL26, RPL35A, RPL5, RPS10, RPS19, RPS24, RPS26, RPS7

Thyroid Cancer Panel (11 genes) Primary Panel (7 genes) APC, CHEK2, DICER1, PRKAR1A, PTEN, RET, TP53
Add-on Preliminary-evidence Genes for Thyroid Cancer (4 genes) MEN1, SDHB, SDHD, WRN

Prostate Cancer Panel 19 genes Primary Panel (12 genes) ATM, BRCA1, BRCA2, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6, NBN, PMS2, TP53
Add-on Preliminary-evidence Genes for Prostate Cancer (7 genes) ATR, BRIP1, FANCA, GEN1, PALB2, RAD51C, RAD51D